A newly developed blood test may soon change how celiac disease is diagnosed. Unlike current methods that often require patients to consume gluten again — risking painful symptoms — this test identifies gluten-reactive immune activity without reintroducing gluten into the diet.
The test works by measuring the immune system’s response to gluten fragments added directly to a blood sample. Specifically, it tracks the release of interleukin‑2, a signaling molecule that indicates T-cell activation. The results are highly accurate and match traditional testing approaches, without the need for invasive procedures or dietary challenges.
This is especially relevant for individuals who have already eliminated gluten from their diet. Until now, they faced a dilemma: reintroduce gluten and risk feeling unwell just to get a diagnosis, or remain undiagnosed. This new approach offers a safe and reliable alternative.
For those in the low-carb, gluten-free, or ketogenic lifestyle, this innovation offers the possibility of clarity without compromise. It protects current dietary choices while giving access to a precise, science-based diagnosis that could shape long-term health decisions.
Source: Elsevier
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